Complete Information on Acinic cell carcinoma with Treatment and Prevention
Acinic cell carcinoma is the fourth most common malignant salivary gland tumor, following mucoepidermoid carcinoma, adenoid cystic carcinoma, and carcinoma ex pleomorphic adenoma; it occurs more frequently than primary squamous cell carcinoma.
Acinic cell carcinoma is a rare, low-grade malignant salivary gland neoplasm. These are malignant tumors of the salivary glands that are dervied from the salivary gland epithelium and characteristically forms glandular acini. It is notable for an unpredictable clinical course with both local recurrence and distant metastase. Approximately, 20% of patients experience local recurrence and 10% distant metastasis, often many years after initial presentation. Pain or tenderness may be present in up to 1/3 of patients. The disease presents as a slow growing mass, sometimes associated with pain or tenderness. A history of exposure to radiation should be sought in patients with salivary gland neoplasms of the larynx or trachea.